Activated Charcoal in Medical Applications, Second Edition by David O. Cooney

By David O. Cooney

Highlighting activated charcoal's nice effectiveness in treating drug overdoses and poisonings in either people and animals, this complete, single-source reference brings jointly very important info from each major examine at the use of activated charcoal for scientific purposes-describing all on hand charcoal items and their features.

Details activated charcoal's skill to minimize the systemic absorption of an unlimited array of substances, chemical compounds, and biochemical substances-including analgesics, antipyretics, sedatives, alkaloids, snake venoms, and bacterial and fungal pollutants.

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Studies in adsorption. I. The adsorption of physiologically active substances by activated charcoal, J. Pharmacol. 42, 169. Sears, Roebuck, and Company (1969). 1908 Catalog No. 117 (reprint), Digest Books, Northfield, Illinois, p. 790. Sjogren, B. and Wallden, E. (1935). The adsorbing power of medicinal charcoal, Svensk. Farm. Tid. 39, 617, 632, 673, 697, 720. Suchy, J. F. and Rice, R. V. (1935). Adsorption of strychnine sulfate by various charcoals and by Lloyd's reagent, J. Am. Pharm. Assoc. 24, 120.

We will mention here only four such studies. Ward and Getzen (1970) have studied the adsorption of three aromatic acidic herbicides as a function of pH, Martin and Iwugo (1982) have examined the pH dependence of the adsorption of organic compounds from sewage effluents, and Wang et al. (1975) have looked at the variation of the adsorption of organics from industrial waste waters with pH. Muller et al. 6 -^ 1 Effect of pH on adsorption of salicylate by activated charcoal. From Cooney, 1992. "i" ' i ' i 1 ~ ~T 1 1 1 CO £L - | / 0 o> k.

The Langmuir Isotherm Equation An adsorption "isotherm" equation is an expression of the relation between the amount of solute adsorbed and the concentration of the solute in the fluid phase, at a given constant temperature. One particular mathematical form of an isotherm which is often found to fit experimental data is the so-called Langmuir isotherm equation. The mathe­ matical form of this equation results from the following development. When a solution is contacted with charcoal and the system is allowed to attain equilibrium, in that equilibrium state the rate at which molecules are adsorbing to the surface is equal to the rate at which molecules are leaving the surface.

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